Phys. Rev. -- Table of Contents (January 2007, 87, (1))

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[Cover Caption]
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Contents: Volume 87, Issue 1; January, 2007. [Index by Author] [Editorial Board]

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Articles

Dagmar Wilhelm, Stephen Palmer, and Peter Koopman: Sex Determination and Gonadal Development in Mammals
Physiol. Rev. 87: 1-28, 2007; doi:10.1152/physrev.00009.2006 [Abstract] [Full Text] [PDF]

Jorgina Satrústegui, Beatriz Pardo, and Araceli del Arco: Mitochondrial Transporters as Novel Targets for Intracellular Calcium Signaling
Physiol. Rev. 87: 29-67, 2007; doi:10.1152/physrev.00005.2006 [Abstract] [Full Text] [PDF]

Kendra J. Greenlee, Zena Werb, and Farrah Kheradmand: Matrix Metalloproteinases in Lung: Multiple, Multifarious, and Multifaceted
Physiol. Rev. 87: 69-98, 2007; doi:10.1152/physrev.00022.2006 [Abstract] [Full Text] [PDF]

Guido Kroemer, Lorenzo Galluzzi, and Catherine Brenner: Mitochondrial Membrane Permeabilization in Cell Death
Physiol. Rev. 87: 99-163, 2007; doi:10.1152/physrev.00013.2006 [Abstract] [Full Text] [PDF]

Bernd Nilius, Grzegorz Owsianik, Thomas Voets, and John A. Peters: Transient Receptor Potential Cation Channels in Disease
Physiol. Rev. 87: 165-217, 2007; doi:10.1152/physrev.00021.2006 [Abstract] [Full Text] [PDF]

Yutaka Maeda, Vrushank Davé, and Jeffrey A. Whitsett: Transcriptional Control of Lung Morphogenesis
Physiol. Rev. 87: 219-244, 2007; doi:10.1152/physrev.00028.2006 [Abstract] [Full Text] [PDF]

Karen Bedard and Karl-Heinz Krause: The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
Physiol. Rev. 87: 245-313, 2007; doi:10.1152/physrev.00044.2005 [Abstract] [Full Text] [PDF]

Pál Pacher, Joseph S. Beckman, and Lucas Liaudet: Nitric Oxide and Peroxynitrite in Health and Disease
Physiol. Rev. 87: 315-424, 2007; doi:10.1152/physrev.00029.2006 [Abstract] [Full Text] [PDF]

Cover

Cover: Role of nitric oxide and peroxynitrite in health and disease. On the one hand, nitric oxide (NO) by activating soluble guanylate cyclase (sGC)-cGMP signal transduction pathway mediates various physiological/beneficial effects involved in tissue protection. On the other hand, under pathological conditions (e.g., stroke, myocardial infarction, chronic heart failure, diabetes, circulatory shock, chronic inflammatory diseases, cancer, and neurodegenerative disorders, etc.), NO and superoxide (·O^-₂) react to form peroxynitrite (ONOO-) which attacks various key biomolecules, eventually leading to cellular dysfunction and tissue injury via multiple mechanisms. Physiological Reviews gratefully acknowledges the significant contribution made by Dr. Pál Pacher in the creation of the cover illustration. See Pacher, Pál, Joseph S. Beckman, and Lucas Liaudet. Physiol Rev 87: 315-424, 2007.