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![]() [Cover Caption] Other Issues: |
Contents:
Volume 84, Issue 1; January, 2004.
[Index by Author] [Editorial Board]
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= article is free immediately upon publication
(all articles are free one year after publication)
Cover: Photograph shows a few of the 500 species of cone snails that produce the Conus peptides that have become standard ligands for ion channels. The top panel shows a necklace recovered from the ruins of the oldest known city, Uruk in Mesopotamia, with shells of two species of Conus, C. ebraeus and C. parvatus. The necklace is now in the Pergamon Museum in Berlin, Germany. The bottom panel shows some cone snail shells. Top row: the glory-of-the-sea cone, Conus gloriamaris, a famous rarity highly prized by shell collectors. Bottom row, from left to right: Conus marmoreus, the marble cone; Conus cedonulli, the matchless cone; Conus imperialis, the imperial cone; Conus purpurascens, the purple cone; Conus magus, the magician's cone; Conus geographus, the geography cone. The geography cone is the species responsible for most documented human fatalities from cone snail stings. A specimen of the matchless cone, Conus cedonulli (literally "I cede to nothing"), once easily outsold a painting by Vermeer at an auction in Amsterdam at the end of the 18th century. A portion of the design of the shell of Conus cedonulli was used as the background. See Terlau, Heinrich, and Baldomero M. Olivera. Physiol Rev 84: 41-68, 2004.
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