Physiol Rev Watch the video to see how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


Physiol. Rev. 84: 1315-1339, 2004; doi:10.1152/physrev.00002.2004
0031-9333/04 $15.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (169)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Brown, M. C.
Right arrow Articles by Turner, C. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Brown, M. C.
Right arrow Articles by Turner, C. E.

Paxillin: Adapting to Change

Michael C. Brown and Christopher E. Turner

Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York

Molecular scaffold or adaptor proteins facilitate precise spatiotemporal regulation and integration of multiple signaling pathways to effect the optimal cellular response to changes in the immediate environment. Paxillin is a multidomain adaptor that recruits both structural and signaling molecules to focal adhesions, sites of integrin engagement with the extracellular matrix, where it performs a critical role in transducing adhesion and growth factor signals to elicit changes in cell migration and gene expression.


Address for reprint requests and other correspondence: C. E. Turner, Dept. of Cell and Developmental Biology, SUNY Upstate Medical University, 750 East Adams St., Syracuse, NY 13210 (E-mail: turnerce{at}upstate.edu)




This article has been cited by other articles:


Home page
Am. J. Respir. Cell Mol. Bio.Home page
A. A. Birukova, I. Cokic, N. Moldobaeva, and K. G. Birukov
Paxillin Is Involved in the Differential Regulation of Endothelial Barrier by HGF and VEGF
Am. J. Respir. Cell Mol. Biol., January 1, 2009; 40(1): 99 - 107.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
A. J. Torres, L. Vasudevan, D. Holowka, and B. A. Baird
Nanomaterials in Medicine Special Feature Sackler Colloquium: Focal adhesion proteins connect IgE receptors to the cytoskeleton as revealed by micropatterned ligand arrays
PNAS, November 11, 2008; 105(45): 17238 - 17244.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
N. Vogt and S. Seiler
The RHO1-specific GTPase-activating Protein LRG1 Regulates Polar Tip Growth in Parallel to Ndr Kinase Signaling in Neurospora
Mol. Biol. Cell, November 1, 2008; 19(11): 4554 - 4569.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
A. A. Birukova, E. Alekseeva, I. Cokic, C. E. Turner, and K. G. Birukov
Cross talk between paxillin and Rac is critical for mediation of barrier-protective effects by oxidized phospholipids
Am J Physiol Lung Cell Mol Physiol, October 1, 2008; 295(4): L593 - L602.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
N. O. Deakin and C. E. Turner
Paxillin comes of age
J. Cell Sci., August 1, 2008; 121(15): 2435 - 2444.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
X. Wang, K. Fukuda, I.-J. Byeon, A. Velyvis, C. Wu, A. Gronenborn, and J. Qin
The Structure of {alpha}-Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly
J. Biol. Chem., July 25, 2008; 283(30): 21113 - 21119.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
Z. M. Zhang, J. A. Simmerman, C. D. Guibao, and J. J. Zheng
GIT1 Paxillin-binding Domain Is a Four-helix Bundle, and It Binds to Both Paxillin LD2 and LD4 Motifs
J. Biol. Chem., July 4, 2008; 283(27): 18685 - 18693.
[Abstract] [Full Text] [PDF]


Home page
Mol. Endocrinol.Home page
S. Kaulfuss, M. Grzmil, B. Hemmerlein, P. Thelen, S. Schweyer, J. Neesen, L. Bubendorf, A. G. Glass, H. Jarry, B. Auber, et al.
Leupaxin, a Novel Coactivator of the Androgen Receptor, Is Expressed in Prostate Cancer and Plays a Role in Adhesion and Invasion of Prostate Carcinoma Cells
Mol. Endocrinol., July 1, 2008; 22(7): 1606 - 1621.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
R. Wade, N. Brimer, and S. Vande Pol
Transformation by Bovine Papillomavirus Type 1 E6 Requires Paxillin
J. Virol., June 15, 2008; 82(12): 5962 - 5966.
[Abstract] [Full Text] [PDF]


Home page
Infect. Immun.Home page
Y. Hasegawa, G. D. Tribble, H. V. Baker, J. J. Mans, M. Handfield, and R. J. Lamont
Role of Porphyromonas gingivalis SerB in Gingival Epithelial Cell Cytoskeletal Remodeling and Cytokine Production
Infect. Immun., June 1, 2008; 76(6): 2420 - 2427.
[Abstract] [Full Text] [PDF]


Home page
J CARDIOVASC PHARMACOL THERHome page
D. D. Tang and Y. Anfinogenova
Physiologic Properties and Regulation of the Actin Cytoskeleton in Vascular Smooth Muscle
Journal of Cardiovascular Pharmacology and Therapeutics, June 1, 2008; 13(2): 130 - 140.
[Abstract] [PDF]


Home page
Pharmacol. Rev.Home page
D. D. Mruk, B. Silvestrini, and C. Y. Cheng
Anchoring Junctions As Drug Targets: Role in Contraceptive Development
Pharmacol. Rev., June 1, 2008; 60(2): 146 - 180.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
J. L. Snider, C. Allison, B. H. Bellaire, R. L. Ferrero, and J. A. Cardelli
The {beta}1 Integrin Activates JNK Independent of CagA, and JNK Activation Is Required for Helicobacter pylori CagA+-induced Motility of Gastric Cancer Cells
J. Biol. Chem., May 16, 2008; 283(20): 13952 - 13963.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
C. K. Augustine, Y. Yoshimoto, M. Gupta, P. A. Zipfel, M. A. Selim, P. Febbo, A. M. Pendergast, W. P. Peters, and D. S. Tyler
Targeting N-Cadherin Enhances Antitumor Activity of Cytotoxic Therapies in Melanoma Treatment
Cancer Res., May 15, 2008; 68(10): 3777 - 3784.
[Abstract] [Full Text] [PDF]


Home page
Physiol. Rev.Home page
C. Le Clainche and M.-F. Carlier
Regulation of Actin Assembly Associated With Protrusion and Adhesion in Cell Migration
Physiol Rev, April 1, 2008; 88(2): 489 - 513.
[Abstract] [Full Text] [PDF]


Home page
DNA ResHome page
T. Tougan, H. Onda, D. Okuzaki, S. Kobayashi, H. Hashimoto, and H. Nojima
Focused Microarray Analysis of Peripheral Mononuclear Blood Cells from Churg-Strauss Syndrome Patients
DNA Res, April 1, 2008; 15(2): 103 - 114.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
D. D. Tang
Intermediate filaments in smooth muscle
Am J Physiol Cell Physiol, April 1, 2008; 294(4): C869 - C878.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
X. Jiao, S. Katiyar, M. Liu, S. C. Mueller, M. P. Lisanti, A. Li, T. G. Pestell, K. Wu, X. Ju, Z. Li, et al.
Disruption of c-Jun Reduces Cellular Migration and Invasion through Inhibition of c-Src and Hyperactivation of ROCK II Kinase
Mol. Biol. Cell, April 1, 2008; 19(4): 1378 - 1390.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
M. Pinar, P. M. Coll, S. A. Rincon, and P. Perez
Schizosaccharomyces pombe Pxl1 Is a Paxillin Homologue That Modulates Rho1 Activity and Participates in Cytokinesis
Mol. Biol. Cell, April 1, 2008; 19(4): 1727 - 1738.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
W. Ge and M. K. Balasubramanian
Pxl1p, a Paxillin-related Protein, Stabilizes the Actomyosin Ring during Cytokinesis in Fission Yeast
Mol. Biol. Cell, April 1, 2008; 19(4): 1680 - 1692.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
K. V. Pajcini, J. H. Pomerantz, O. Alkan, R. Doyonnas, and H. M. Blau
Myoblasts and macrophages share molecular components that contribute to cell-cell fusion
J. Cell Biol., March 5, 2008; 180(5): 1005 - 1019.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
C. Li, B. Ge, M. Nicotra, J. N. H. Stern, H. D. Kopcow, X. Chen, and J. L. Strominger
JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity
PNAS, February 26, 2008; 105(8): 3017 - 3022.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
E. A. Pickett, G. S. Olsen, and M. D. Tallquist
Disruption of PDGFR{alpha}-initiated PI3K activation and migration of somite derivatives leads to spina bifida
Development, February 1, 2008; 135(3): 589 - 598.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
R. Srinivasan, S. Forman, R. A. Quinlan, J. Ohanian, and V. Ohanian
Regulation of contractility by Hsp27 and Hic-5 in rat mesenteric small arteries
Am J Physiol Heart Circ Physiol, February 1, 2008; 294(2): H961 - H969.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
C. Badowski, G. Pawlak, A. Grichine, A. Chabadel, C. Oddou, P. Jurdic, M. Pfaff, C. Albiges-Rizo, and M. R. Block
Paxillin Phosphorylation Controls Invadopodia/Podosomes Spatiotemporal Organization
Mol. Biol. Cell, February 1, 2008; 19(2): 633 - 645.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
A. Efimov, N. Schiefermeier, I. Grigoriev, M. C. Brown, C. E. Turner, J. V. Small, and I. Kaverina
Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites
J. Cell Sci., January 15, 2008; 121(2): 196 - 204.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
Y. Miyamoto, J. Yamauchi, J. R. Chan, A. Okada, Y. Tomooka, S.-i. Hisanaga, and A. Tanoue
Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin
J. Cell Sci., December 15, 2007; 120(24): 4355 - 4366.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
J. D. Humphries, P. Wang, C. Streuli, B. Geiger, M. J. Humphries, and C. Ballestrem
Vinculin controls focal adhesion formation by direct interactions with talin and actin
J. Cell Biol., December 3, 2007; 179(5): 1043 - 1057.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
V. Chew and K.-P. Lam
Leupaxin Negatively Regulates B Cell Receptor Signaling
J. Biol. Chem., September 14, 2007; 282(37): 27181 - 27191.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
C. M. Rembold, A. D. Tejani, M. L. Ripley, and S. Han
Paxillin phosphorylation, actin polymerization, noise temperature, and the sustained phase of swine carotid artery contraction
Am J Physiol Cell Physiol, September 1, 2007; 293(3): C993 - C1002.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
E. Manevich, V. Grabovsky, S. W. Feigelson, and R. Alon
Talin 1 and Paxillin Facilitate Distinct Steps in Rapid VLA-4-mediated Adhesion Strengthening to Vascular Cell Adhesion Molecule 1
J. Biol. Chem., August 31, 2007; 282(35): 25338 - 25348.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Pathol.Home page
M. Alderliesten, M. de Graauw, J. Oldenampsen, Y. Qin, C. Pont, L. van Buren, and B. van de Water
Extracellular Signal-Regulated Kinase Activation during Renal Ischemia/Reperfusion Mediates Focal Adhesion Dissolution and Renal Injury
Am. J. Pathol., August 1, 2007; 171(2): 452 - 462.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
K. Lange, M. Kammerer, M. E. Hegi, S. Grotegut, A. Dittmann, W. Huang, E. Fluri, G. W. Yip, M. Gotte, C. Ruiz, et al.
Endothelin Receptor Type B Counteracts Tenascin-C-Induced Endothelin Receptor Type A-Dependent Focal Adhesion and Actin Stress Fiber Disorganization
Cancer Res., July 1, 2007; 67(13): 6163 - 6173.
[Abstract] [Full Text] [PDF]


Home page
EndocrinologyHome page
D. B. Speert, A. T. M. Konkle, S. L. Zup, J. M. Schwarz, C. Shiroor, M. E. Taylor, and M. M. McCarthy
Focal Adhesion Kinase and Paxillin: Novel Regulators of Brain Sexual Differentiation?
Endocrinology, July 1, 2007; 148(7): 3391 - 3401.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
C. Avraamides, M. E. Bromberg, J. P. Gaughan, S. M. Thomas, A. Y. Tsygankov, and T. S. Panetti
Hic-5 promotes endothelial cell migration to lysophosphatidic acid
Am J Physiol Heart Circ Physiol, July 1, 2007; 293(1): H193 - H203.
[Abstract] [Full Text] [PDF]


Home page
Mol Cancer ResHome page
J. Huang, J.-T. Liang, H.-C. Huang, T.-L. Shen, H.-Y. Chen, N.-Y. Lin, M.-I. Che, W.-C. Lin, and M.-C. Huang
{beta}1,4-N-Acetylgalactosaminyltransferase III Enhances Malignant Phenotypes of Colon Cancer Cells
Mol. Cancer Res., June 1, 2007; 5(6): 543 - 552.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
S. N. Sahu, S. Nunez, G. Bai, and A. Gupta
Interaction of Pyk2 and PTP-PEST with leupaxin in prostate cancer cells
Am J Physiol Cell Physiol, June 1, 2007; 292(6): C2288 - C2296.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
D. M. Nikolic, J. Cholewa, C. Gass, M. C. Gong, and S. R. Post
Class A scavenger receptor-mediated cell adhesion requires the sequential activation of Lyn and PI3-kinase
Am J Physiol Cell Physiol, April 1, 2007; 292(4): C1450 - C1458.
[Abstract] [Full Text] [PDF]


Home page
Sci SignalHome page
Y.-l. Wang
Flux at Focal Adhesions: Slippage Clutch, Mechanical Gauge, or Signal Depot
Sci. Signal., March 13, 2007; 2007(377): pe10 - pe10.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
A. Hajdo-Milasinovic, S. I. J. Ellenbroek, S. van Es, B. van der Vaart, and J. G. Collard
Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells
J. Cell Sci., February 15, 2007; 120(4): 555 - 566.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
M. Halle, Y.-C. Liu, S. Hardy, J.-F. Theberge, C. Blanchetot, A. Bourdeau, T.-C. Meng, and M. L. Tremblay
Caspase-3 Regulates Catalytic Activity and Scaffolding Functions of the Protein Tyrosine Phosphatase PEST, a Novel Modulator of the Apoptotic Response
Mol. Cell. Biol., February 1, 2007; 27(3): 1172 - 1190.
[Abstract] [Full Text] [PDF]


Home page
J. Pharmacol. Exp. Ther.Home page
R. G. Deschesnes, A. Patenaude, J. L. C. Rousseau, J. S. Fortin, C. Ricard, M.-F. Cote, J. Huot, R. C.-Gaudreault, and E. Petitclerc
Microtubule-Destabilizing Agents Induce Focal Adhesion Structure Disorganization and Anoikis in Cancer Cells
J. Pharmacol. Exp. Ther., February 1, 2007; 320(2): 853 - 864.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
R. Zaidel-Bar, R. Milo, Z. Kam, and B. Geiger
A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions
J. Cell Sci., January 1, 2007; 120(1): 137 - 148.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
S. N. Sahu, M. A. Khadeer, B. W. Robertson, S. M. Nunez, G. Bai, and A. Gupta
Association of leupaxin with Src in osteoclasts
Am J Physiol Cell Physiol, January 1, 2007; 292(1): C581 - C590.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
M. Rasar, D. B. DeFranco, and S. R. Hammes
Paxillin Regulates Steroid-triggered Meiotic Resumption in Oocytes by Enhancing an All-or-None Positive Feedback Kinase Loop
J. Biol. Chem., December 22, 2006; 281(51): 39455 - 39464.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
J. Guo, A. Sabri, H. Elouardighi, V. Rybin, and S. F. Steinberg
{alpha}1-Adrenergic Receptors Activate AKT via a Pyk2/PDK-1 Pathway That Is Tonically Inhibited by Novel Protein Kinase C Isoforms in Cardiomyocytes
Circ. Res., December 8, 2006; 99(12): 1367 - 1375.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
Q.-F. Li, A. M. Spinelli, R. Wang, Y. Anfinogenova, H. A. Singer, and D. D. Tang
Critical Role of Vimentin Phosphorylation at Ser-56 by p21-activated Kinase in Vimentin Cytoskeleton Signaling
J. Biol. Chem., November 10, 2006; 281(45): 34716 - 34724.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
M. Meriane, S. Duhamel, L. Lejeune, J. Galipeau, and B. Annabi
Cooperation of Matrix Metalloproteinases with the RhoA/Rho Kinase and Mitogen-Activated Protein Kinase Kinase-1/Extracellular Signal-Regulated Kinase Signaling Pathways Is Required for the Sphingosine-1-Phosphate-Induced Mobilization of Marrow-Derived Stromal Cells
Stem Cells, November 1, 2006; 24(11): 2557 - 2565.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
Y. Tatsumi, Y.-Y. Cho, Z. He, H. Mizuno, H. Seok Choi, A. M. Bode, and Z. Dong
Involvement of the Paxillin Pathway in JB6 Cl41 Cell Transformation
Cancer Res., June 1, 2006; 66(11): 5968 - 5974.
[Abstract] [Full Text] [PDF]


Home page
Clin. Cancer Res.Home page
P. M.F. Siesser and S. K. Hanks
The Signaling and Biological Implications of FAK Overexpression in Cancer.
Clin. Cancer Res., June 1, 2006; 12(11): 3233 - 3237.
[Full Text] [PDF]


Home page
JCBHome page
A. Nayal, D. J. Webb, C. M. Brown, E. M. Schaefer, M. Vicente-Manzanares, and A. R. Horwitz
Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics
J. Cell Biol., May 22, 2006; 173(4): 587 - 589.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
M. Leslie
Integrin signal transduction
J. Cell Biol., April 24, 2006; 173(2): 150a - 150a.
[Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
X. Cai, M. Li, J. Vrana, and M. D. Schaller
Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement.
Mol. Cell. Biol., April 1, 2006; 26(7): 2857 - 2868.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
L. H. Romer, K. G. Birukov, and J. G.N. Garcia
Focal Adhesions: Paradigm for a Signaling Nexus
Circ. Res., March 17, 2006; 98(5): 606 - 616.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
M. A. Partridge, F. S. David, and E. E. Marcantonio
Displacement of the {beta} cytoplasmic domain recovers focal adhesion formation, cytoskeletal organization and motility in swapped integrin chimeras
J. Cell Sci., March 15, 2006; 119(6): 1175 - 1183.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
C. Ballestrem, N. Erez, J. Kirchner, Z. Kam, A. Bershadsky, and B. Geiger
Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer
J. Cell Sci., March 1, 2006; 119(5): 866 - 875.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
J. P. ten Klooster, Z. M. Jaffer, J. Chernoff, and P. L. Hordijk
Targeting and activation of Rac1 are mediated by the exchange factor {beta}-Pix
J. Cell Biol., February 27, 2006; 172(5): 759 - 769.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
M. L. Moeller, Y. Shi, L. F. Reichardt, and I. M. Ethell
EphB Receptors Regulate Dendritic Spine Morphogenesis through the Recruitment/Phosphorylation of Focal Adhesion Kinase and RhoA Activation
J. Biol. Chem., January 20, 2006; 281(3): 1587 - 1598.
[Abstract] [Full Text] [PDF]


Home page
Physiol. Rev.Home page
D. Mehta and A. B. Malik
Signaling Mechanisms Regulating Endothelial Permeability
Physiol Rev, January 1, 2006; 86(1): 279 - 367.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
R. Alon, S. W. Feigelson, E. Manevich, D. M. Rose, J. Schmitz, D. R. Overby, E. Winter, V. Grabovsky, V. Shinder, B. D. Matthews, et al.
{alpha}4{beta}1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the {alpha}4-cytoplasmic domain
J. Cell Biol., December 19, 2005; 171(6): 1073 - 1084.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
J. S. Jamieson, D. A. Tumbarello, M. Halle, M. C. Brown, M. L. Tremblay, and C. E. Turner
Paxillin is essential for PTP-PEST-dependent regulation of cell spreading and motility: a role for paxillin kinase linker
J. Cell Sci., December 15, 2005; 118(24): 5835 - 5847.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
D. J. Webb, M. J. Schroeder, C. J. Brame, L. Whitmore, J. Shabanowitz, D. F. Hunt, and A. R. Horwitz
Paxillin phosphorylation sites mapped by mass spectrometry
J. Cell Sci., November 1, 2005; 118(21): 4925 - 4929.
[Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
K. K. Lu, S. E. Armstrong, R. Ginnan, and H. A. Singer
Adhesion-dependent activation of CaMKII and regulation of ERK activation in vascular smooth muscle
Am J Physiol Cell Physiol, November 1, 2005; 289(5): C1343 - C1350.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
T. Bukahrova, G. Weijer, L. Bosgraaf, D. Dormann, P. J. van Haastert, and C. J. Weijer
Paxillin is required for cell-substrate adhesion, cell sorting and slug migration during Dictyostelium development
J. Cell Sci., September 15, 2005; 118(18): 4295 - 4310.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
M. C. Mendoza, F. Du, N. Iranfar, N. Tang, H. Ma, W. F. Loomis, and R. A. Firtel
Loss of SMEK, a Novel, Conserved Protein, Suppresses mek1 Null Cell Polarity, Chemotaxis, and Gene Expression Defects
Mol. Cell. Biol., September 1, 2005; 25(17): 7839 - 7853.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
M. C. Brown, L. A. Cary, J. S. Jamieson, J. A. Cooper, and C. E. Turner
Src and FAK Kinases Cooperate to Phosphorylate Paxillin Kinase Linker, Stimulate Its Focal Adhesion Localization, and Regulate Cell Spreading and Protrusiveness
Mol. Biol. Cell, September 1, 2005; 16(9): 4316 - 4328.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
D. P. LaLonde, M. C. Brown, B. P. Bouverat, and C. E. Turner
Actopaxin Interacts with TESK1 to Regulate Cell Spreading on Fibronectin
J. Biol. Chem., June 3, 2005; 280(22): 21680 - 21688.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2004 by the American Physiological Society.