Physiol Rev Information on EB 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Physiol. Rev. 84: 1-39, 2004; doi:10.1152/physrev.00013.2003
0031-9333/04 $15.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (168)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by CEULEMANS, H.
Right arrow Articles by BOLLEN, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by CEULEMANS, H.
Right arrow Articles by BOLLEN, M.

Functional Diversity of Protein Phosphatase-1, a Cellular Economizer and Reset Button

HUGO CEULEMANS and MATHIEU BOLLEN

Afdeling Biochemie, Faculteit Geneeskunde, Katholieke Universiteit Leuven, Leuven, Belgium

Ceulemans, Hugo, and Mathieu Bollen. Functional Diversity of Protein Phosphatase-1, a Cellular Economizer and Reset Button. Physiol Rev 84: 1–39, 2004; 10.1152/physrev.00013.2003.—The protein serine/threonine phosphatase protein phosphatase-1 (PP1) is a ubiquitous eukaryotic enzyme that regulates a variety of cellular processes through the dephosphorylation of dozens of substrates. This multifunctionality of PP1 relies on its association with a host of function-specific targetting and substrate-specifying proteins. In this review we discuss how PP1 affects the biochemistry and physiology of eukaryotic cells. The picture of PP1 that emerges from this analysis is that of a "green" enzyme that promotes the rational use of energy, the recycling of protein factors, and a reversal of the cell to a basal and/or energy-conserving state. Thus PP1 promotes a shift to the more energy-efficient fuels when nutrients are abundant and stimulates the storage of energy in the form of glycogen. PP1 also enables the relaxation of actomyosin fibers, the return to basal patterns of protein synthesis, and the recycling of transcription and splicing factors. In addition, PP1 plays a key role in the recovery from stress but promotes apoptosis when cells are damaged beyond repair. Furthermore, PP1 downregulates ion pumps and transporters in various tissues and ion channels that are involved in the excitation of neurons. Finally, PP1 promotes the exit from mitosis and maintains cells in the G1 or G2 phases of the cell cycle.

Address for reprint requests and other correspondence: M. Bollen, Afdeling Biochemie, Campus Gasthuisberg KULeuven, Herestraat 49, B-3000 Leuven, Belgium (E-mail: Mathieu.Bollen{at}med.kuleuven.ac.be).




This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
R. Ayon, W. Sones, A. S. Forrest, M. Wiwchar, M. L. Valencik, A. R. Sanguinetti, B. A. Perrino, I. A. Greenwood, and N. Leblanc
Complex Phosphatase Regulation of Ca2+-activated Cl- Currents in Pulmonary Arterial Smooth Muscle Cells
J. Biol. Chem., November 20, 2009; 284(47): 32507 - 32521.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
K. Koshibu, J. Graff, M. Beullens, F. D. Heitz, D. Berchtold, H. Russig, M. Farinelli, M. Bollen, and I. M. Mansuy
Protein Phosphatase 1 Regulates the Histone Code for Long-Term Memory
J. Neurosci., October 14, 2009; 29(41): 13079 - 13089.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Chen, C. T. Kesler, B. M. Paschal, and S. P. Balk
Androgen Receptor Phosphorylation and Activity Are Regulated by an Association with Protein Phosphatase 1
J. Biol. Chem., September 18, 2009; 284(38): 25576 - 25584.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
U. von Plehwe, U. Berndt, C. Conz, M. Chiabudini, E. Fitzke, A. Sickmann, A. Petersen, D. Pfeifer, and S. Rospert
The Hsp70 homolog Ssb is essential for glucose sensing via the SNF1 kinase network
Genes & Dev., September 1, 2009; 23(17): 2102 - 2115.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
R. L. S. Perry, C. Yang, N. Soora, J. Salma, M. Marback, L. Naghibi, H. Ilyas, J. Chan, J. W. Gordon, and J. C. McDermott
Direct Interaction between Myocyte Enhancer Factor 2 (MEF2) and Protein Phosphatase 1{alpha} Represses MEF2-Dependent Gene Expression
Mol. Cell. Biol., June 15, 2009; 29(12): 3355 - 3366.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Pharmacol.Home page
J. L. McConnell and B. E. Wadzinski
Targeting Protein Serine/Threonine Phosphatases for Drug Development
Mol. Pharmacol., June 1, 2009; 75(6): 1249 - 1261.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Popescu, Z. Gurel, T. Ronni, C. Song, K. Y. Hung, K. J. Payne, and S. Dovat
Ikaros Stability and Pericentromeric Localization Are Regulated by Protein Phosphatase 1
J. Biol. Chem., May 15, 2009; 284(20): 13869 - 13880.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. Takemiya, C. Ariyoshi, and K.-i. Shimazaki
Identification and Functional Characterization of Inhibitor-3, a Regulatory Subunit of Protein Phosphatase 1 in Plants
Plant Physiology, May 1, 2009; 150(1): 144 - 156.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
M. V. Bardina, P. V. Lidsky, E. V. Sheval, K. V. Fominykh, F. J. M. van Kuppeveld, V. Y. Polyakov, and V. I. Agol
Mengovirus-Induced Rearrangement of the Nuclear Pore Complex: Hijacking Cellular Phosphorylation Machinery
J. Virol., April 1, 2009; 83(7): 3150 - 3161.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
M. Rogne, A. J. Stokka, K. Tasken, P. Collas, and T. Kuntziger
Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network
Hum. Mol. Genet., March 1, 2009; 18(5): 978 - 987.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
T. Saino and E. L. Watson
Inhibition of serine/threonine phosphatase enhances arachidonic acid-induced [Ca2+]i via protein kinase A
Am J Physiol Cell Physiol, January 1, 2009; 296(1): C88 - C96.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
N. Tanuma, S.-E. Kim, M. Beullens, Y. Tsubaki, S. Mitsuhashi, M. Nomura, T. Kawamura, K. Isono, H. Koseki, M. Sato, et al.
Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)
J. Biol. Chem., December 19, 2008; 283(51): 35805 - 35814.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
J. Davis, M. V. Westfall, D. Townsend, M. Blankinship, T. J. Herron, G. Guerrero-Serna, W. Wang, E. Devaney, and J. M. Metzger
Designing Heart Performance by Gene Transfer
Physiol Rev, October 1, 2008; 88(4): 1567 - 1651.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Zhang, M. Liao, and M. L. Dufau
Unlocking Repression of the Human Luteinizing Hormone Receptor Gene by Trichostatin A-induced Cell-specific Phosphatase Release
J. Biol. Chem., August 29, 2008; 283(35): 24039 - 24046.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
W. Wang, C. Cronmiller, and D. L. Brautigan
Maternal Phosphatase Inhibitor-2 Is Required for Proper Chromosome Segregation and Mitotic Synchrony During Drosophila Embryogenesis
Genetics, August 1, 2008; 179(4): 1823 - 1833.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H.-S. Huang and E. Y. C. Lee
Protein Phosphatase-1 Inhibitor-3 Is an in Vivo Target of Caspase-3 and Participates in the Apoptotic Response
J. Biol. Chem., June 27, 2008; 283(26): 18135 - 18146.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
L. E. Vinge, P. W. Raake, and W. J. Koch
Gene Therapy in Heart Failure
Circ. Res., June 20, 2008; 102(12): 1458 - 1470.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
L. C. Carmody, A. J. Baucum II, M. A. Bass, and R. J. Colbran
Selective targeting of the {gamma}1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin
FASEB J, June 1, 2008; 22(6): 1660 - 1671.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
M. Zhong, D. A. Murtazina, J. Phillips, C.-Y. Ku, and B. M. Sanborn
Multiple Signals Regulate Phospholipase CBeta3 in Human Myometrial Cells
Biol Reprod, June 1, 2008; 78(6): 1007 - 1017.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
X. Wang, B. Liu, N. Li, H. Li, J. Qiu, Y. Zhang, and X. Cao
IPP5, a Novel Protein Inhibitor of Protein Phosphatase 1, Promotes G1/S Progression in a Thr-40-dependent Manner
J. Biol. Chem., May 2, 2008; 283(18): 12076 - 12084.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
J. P. Bharucha, J. R. Larson, L. Gao, L. K. Daves, and K. Tatchell
Ypi1, a Positive Regulator of Nuclear Protein Phosphatase Type 1 Activity in Saccharomyces cerevisiae
Mol. Biol. Cell, March 1, 2008; 19(3): 1032 - 1045.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Stamm
Regulation of Alternative Splicing by Reversible Protein Phosphorylation
J. Biol. Chem., January 18, 2008; 283(3): 1223 - 1227.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. R. Gunawardena, B. L. Ruis, J. A. Meyer, M. Kapoor, and K. F. Conklin
NOM1 Targets Protein Phosphatase I to the Nucleolus
J. Biol. Chem., January 4, 2008; 283(1): 398 - 404.
[Abstract] [Full Text] [PDF]

Home page
 MicrobiologyHome page
Y.-E Choi and W.-B. Shim
Functional characterization of Fusarium verticillioides CPP1, a gene encoding a putative protein phosphatase 2A catalytic subunit
Microbiology, January 1, 2008; 154(1): 326 - 336.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
T. Novoyatleva, B. Heinrich, Y. Tang, N. Benderska, M. E.R. Butchbach, C. L. Lorson, M. A. Lorson, C. Ben-Dov, P. Fehlbaum, L. Bracco, et al.
Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing
Hum. Mol. Genet., January 1, 2008; 17(1): 52 - 70.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
I. Alvarez-Tabares, A. Grallert, J.-M. Ortiz, and I. M. Hagan
Schizosaccharomyces pombe protein phosphatase 1 in mitosis, endocytosis and a partnership with Wsh3/Tea4 to control polarised growth
J. Cell Sci., October 15, 2007; 120(20): 3589 - 3601.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. D. Hurley, J. Yang, L. Zhang, K. D. Goodwin, Q. Zou, M. Cortese, A. K. Dunker, and A. A. DePaoli-Roach
Structural Basis for Regulation of Protein Phosphatase 1 by Inhibitor-2
J. Biol. Chem., September 28, 2007; 282(39): 28874 - 28883.
[Abstract] [Full Text] [PDF]

Home page
 Eukaryot CellHome page
W. Daher, G. Oria, S. Fauquenoy, K. Cailliau, E. Browaeys, S. Tomavo, and J. Khalife
A Toxoplasma gondii Leucine-Rich Repeat Protein Binds Phosphatase Type 1 Protein and Negatively Regulates Its Activity
Eukaryot. Cell, September 1, 2007; 6(9): 1606 - 1617.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. A. Gibbons, L. Kozubowski, K. Tatchell, and S. Shenolikar
Expression of Human Protein Phosphatase-1 in Saccharomyces cerevisiae Highlights the Role of Phosphatase Isoforms in Regulating Eukaryotic Functions
J. Biol. Chem., July 27, 2007; 282(30): 21838 - 21847.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
Y. Fang, S. Sathyanarayanan, and A. Sehgal
Post-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1)
Genes & Dev., June 15, 2007; 21(12): 1506 - 1518.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Eto, J. Kirkbride, E. Elliott, S. H. Lo, and D. L. Brautigan
Association of the Tensin N-terminal Protein-tyrosine Phosphatase Domain with the {alpha} Isoform of Protein Phosphatase-1 in Focal Adhesions
J. Biol. Chem., June 15, 2007; 282(24): 17806 - 17815.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
J. Kirchner, S. Gross, D. Bennett, and L. Alphey
Essential, Overlapping and Redundant Roles of the Drosophila Protein Phosphatase 1{alpha} and 1{beta} Genes
Genetics, May 1, 2007; 176(1): 273 - 281.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
M. Parra, T. Mahmoudi, and E. Verdin
Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes
Genes & Dev., March 15, 2007; 21(6): 638 - 643.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
F. Kuroda, J. Moss, and M. Vaughan
Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1{gamma}
PNAS, February 27, 2007; 104(9): 3201 - 3206.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
L. Pedelini, M. Marquina, J. Arino, A. Casamayor, L. Sanz, M. Bollen, P. Sanz, and M. A. Garcia-Gimeno
YPI1 and SDS22 Proteins Regulate the Nuclear Localization and Function of Yeast Type 1 Phosphatase Glc7
J. Biol. Chem., February 2, 2007; 282(5): 3282 - 3292.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
D. Vander Mierde, D. Scheuner, R. Quintens, R. Patel, B. Song, K. Tsukamoto, M. Beullens, R. J. Kaufman, M. Bollen, and F. C. Schuit
Glucose Activates a Protein Phosphatase-1-Mediated Signaling Pathway to Enhance Overall Translation in Pancreatic {beta}-Cells
Endocrinology, February 1, 2007; 148(2): 609 - 617.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
J. Han, L. Han, P. Tiwari, Z. Wen, and J. Q. Zheng
Spatial targeting of type II protein kinase A to filopodia mediates the regulation of growth cone guidance by cAMP
J. Cell Biol., January 1, 2007; 176(1): 101 - 111.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. A. Worby, M. S. Gentry, and J. E. Dixon
Laforin, a Dual Specificity Phosphatase That Dephosphorylates Complex Carbohydrates
J. Biol. Chem., October 13, 2006; 281(41): 30412 - 30418.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Mukherji, R. Bell, L. Supekova, Y. Wang, A. P. Orth, S. Batalov, L. Miraglia, D. Huesken, J. Lange, C. Martin, et al.
Genome-wide functional analysis of human cell-cycle regulators
PNAS, October 3, 2006; 103(40): 14819 - 14824.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Takemiya, T. Kinoshita, M. Asanuma, and K.-i. Shimazaki
Protein phosphatase 1 positively regulates stomatal opening in response to blue light in Vicia faba
PNAS, September 5, 2006; 103(36): 13549 - 13554.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
J. Lartey, A. Gampel, J. Pawade, H. Mellor, and A. L. Bernal
Expression of RND Proteins in Human Myometrium
Biol Reprod, September 1, 2006; 75(3): 452 - 461.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
A. El-Armouche, P. Boknik, T. Eschenhagen, L. Carrier, M. Knaut, U. Ravens, and D. Dobrev
Molecular Determinants of Altered Ca2+ Handling in Human Chronic Atrial Fibrillation
Circulation, August 15, 2006; 114(7): 670 - 680.
[Abstract] [Full Text] [PDF]

Home page
 J Med MicrobiolHome page
H. Andersson, B. Hartmanova, P. Ryden, L. Noppa, L. Naslund, and A. Sjostedt
A microarray analysis of the murine macrophage response to infection with Francisella tularensis LVS.
J. Med. Microbiol., August 1, 2006; 55(Pt 8): 1023 - 1033.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
A. Cheng, M. Zhang, S. M. Crosson, Z. Q. Bao, and A. R. Saltiel
Regulation of the Mouse Protein Targeting to Glycogen (PTG) Promoter by the FoxA2 Forkhead Protein and by 3',5'-Cyclic Adenosine 5'-Monophosphate in H4IIE Hepatoma Cells
Endocrinology, July 1, 2006; 147(7): 3606 - 3612.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
B. A. Pinsky, C. V. Kotwaliwale, S. Y. Tatsutani, C. A. Breed, and S. Biggins
Glc7/Protein phosphatase 1 regulatory subunits can oppose the ipl1/aurora protein kinase by redistributing glc7.
Mol. Cell. Biol., April 1, 2006; 26(7): 2648 - 2660.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
L. Trinkle-Mulcahy, J. Andersen, Y. W. Lam, G. Moorhead, M. Mann, and A. I. Lamond
Repo-Man recruits PP1{gamma} to chromatin and is essential for cell viability
J. Cell Biol., February 27, 2006; 172(5): 679 - 692.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
J. R. Bordelon, Y. Smith, A. C. Nairn, R. J. Colbran, P. Greengard, and E. C. Muly
Differential Localization of Protein Phosphatase-1{alpha}, {beta} and {gamma}1 Isoforms in Primate Prefrontal Cortex
Cereb Cortex, December 1, 2005; 15(12): 1928 - 1937.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. J. Van Kanegan, D. G. Adams, B. E. Wadzinski, and S. Strack
Distinct Protein Phosphatase 2A Heterotrimers Modulate Growth Factor Signaling to Extracellular Signal-regulated Kinases and Akt
J. Biol. Chem., October 28, 2005; 280(43): 36029 - 36036.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
P. A. Knepper, A. M. Miller, J. Choi, R. D. Wertz, M. J. Nolan, W. Goossens, S. Whitmer, B. Y. J. T. Yue, R. Ritch, J. M. Liebmann, et al.
Hypophosphorylation of Aqueous Humor sCD44 and Primary Open-Angle Glaucoma
Invest. Ophthalmol. Vis. Sci., August 1, 2005; 46(8): 2829 - 2837.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. A. Gibbons, D. C. Weiser, and S. Shenolikar
Importance of a Surface Hydrophobic Pocket on Protein Phosphatase-1 Catalytic Subunit in Recognizing Cellular Regulators
J. Biol. Chem., April 22, 2005; 280(16): 15903 - 15911.
[Abstract] [Full Text] [PDF]

Home page
 Sci SignalHome page
S. R. Salton
Protein Phosphatases
Sci. Signal., March 1, 2005; 2005(273): tr8 - tr8.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
B. Lesage, M. Beullens, M. Nuytten, A. Van Eynde, S. Keppens, B. Himpens, and M. Bollen
Interactor-mediated Nuclear Translocation and Retention of Protein Phosphatase-1
J. Biol. Chem., December 31, 2004; 279(53): 55978 - 55984.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. C. Weiser, S. Sikes, S. Li, and S. Shenolikar
The Inhibitor-1 C Terminus Facilitates Hormonal Regulation of Cellular Protein Phosphatase-1: FUNCTIONAL IMPLICATIONS FOR INHIBITOR-1 ISOFORMS
J. Biol. Chem., November 19, 2004; 279(47): 48904 - 48914.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
N. A. Tountas and D. L. Brautigan
Migration and retraction of endothelial and epithelial cells require PHI-1, a specific protein-phosphatase-1 inhibitor protein
J. Cell Sci., November 15, 2004; 117(24): 5905 - 5912.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
R. J. Colbran
Protein Phosphatases and Calcium/Calmodulin-Dependent Protein Kinase II-Dependent Synaptic Plasticity
J. Neurosci., September 29, 2004; 24(39): 8404 - 8409.
[Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. D. Prickett and D. L. Brautigan
Overlapping Binding Sites in Protein Phosphatase 2A for Association with Regulatory A and {alpha}-4 (mTap42) Subunits
J. Biol. Chem., September 10, 2004; 279(37): 38912 - 38920.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
A. Van Eynde, M. Nuytten, M. Dewerchin, L. Schoonjans, S. Keppens, M. Beullens, L. Moons, P. Carmeliet, W. Stalmans, and M. Bollen
The Nuclear Scaffold Protein NIPP1 Is Essential for Early Embryonic Development and Cell Proliferation
Mol. Cell. Biol., July 1, 2004; 24(13): 5863 - 5874.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Eto, T. Kitazawa, and D. L. Brautigan
Phosphoprotein inhibitor CPI-17 specificity depends on allosteric regulation of protein phosphatase-1 by regulatory subunits
PNAS, June 15, 2004; 101(24): 8888 - 8893.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2004 by the American Physiological Society.