Physiol Rev Ad Instruments
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Physiol. Rev. 82: 923-944, 2002; doi:10.1152/physrev.00014.2002
0031-9333/02 $15.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vasudevan, N.
Right arrow Articles by Pfaff, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vasudevan, N.
Right arrow Articles by Pfaff, D.

Physiological Reviews, Vol. 82, No. 4, October 2002, pp. 923-944; 10.1152/physrev.00014.2002.
Copyright ©2002 by the American Physiological Society

Estrogen and Thyroid Hormone Receptor Interactions: Physiological Flexibility by Molecular Specificity

Nandini Vasudevan, Sonoko Ogawa, and Donald Pfaff

Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, New York

Vasudevan, Nandini, Sonoko Ogawa, and Donald Pfaff. Estrogen and Thyroid Hormone Receptor Interactions: Physiological Flexibility by Molecular Specificity. Physiol. Rev. 82: 923-944, 2002.The influence of thyroid hormone on estrogen actions has been demonstrated both in vivo and in vitro. In transient transfection assays, the effects of liganded thyroid hormone receptors (TR) on transcriptional facilitation by estrogens bound to estrogen receptors (ER) display specificity according to the following: 1) ER isoform, 2) TR isoform, 3) the promoter through which transcriptional facilitation occurs, and 4) cell type. Some of these molecular phenomena may be related to thyroid hormone signaling of seasonal limitations upon reproduction. The various combinations of these molecular interactions provide multiple and flexible opportunities for relations between two major hormonal systems important for neuroendocrine feedbacks and reproductive behaviors.




This article has been cited by other articles:


Home page
 J EndocrinolHome page
K. Nagayama, S. Sasaki, A. Matsushita, K. Ohba, H. Iwaki, H. Matsunaga, S. Suzuki, H. Misawa, K. Ishizuka, Y. Oki, et al.
Inhibition of GATA2-dependent transactivation of the TSH{beta} gene by ligand-bound estrogen receptor {alpha}
J. Endocrinol., October 1, 2008; 199(1): 113 - 125.
[Abstract] [Full Text] [PDF]

Home page
 J EndocrinolHome page
J Kwakkel, O Chassande, H C van Beeren, W M Wiersinga, and A Boelen
Lacking thyroid hormone receptor {beta} gene does not influence alterations in peripheral thyroid hormone metabolism during acute illness
J. Endocrinol., April 1, 2008; 197(1): 151 - 158.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
F. Flamant, K. Gauthier, and J. Samarut
Thyroid Hormones Signaling Is Getting More Complex: STORMs Are Coming
Mol. Endocrinol., February 1, 2007; 21(2): 321 - 333.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
S. Yasuo, N. Nakao, S. Ohkura, M. Iigo, S. Hagiwara, A. Goto, H. Ando, T. Yamamura, M. Watanabe, T. Watanabe, et al.
Long-Day Suppressed Expression of Type 2 Deiodinase Gene in the Mediobasal Hypothalamus of the Saanen Goat, a Short-Day Breeder: Implication for Seasonal Window of Thyroid Hormone Action on Reproductive Neuroendocrine Axis
Endocrinology, January 1, 2006; 147(1): 432 - 440.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
H.-Y. Tang, H.-Y. Lin, S. Zhang, F. B. Davis, and P. J. Davis
Thyroid Hormone Causes Mitogen-Activated Protein Kinase-Dependent Phosphorylation of the Nuclear Estrogen Receptor
Endocrinology, July 1, 2004; 145(7): 3265 - 3272.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
M. C. Farach-Carson and P. J. Davis
Steroid Hormone Interactions with Target Cells: Cross Talk between Membrane and Nuclear Pathways
J. Pharmacol. Exp. Ther., December 1, 2003; 307(3): 839 - 845.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
S. Incerpi, S. D'Arezzo, M. Marino, R. Musanti, V. Pallottini, A. Pascolini, and A. Trentalance
Short-Term Activation by Low 17{beta}-Estradiol Concentrations of the Na+/H+ Exchanger in Rat Aortic Smooth Muscle Cells: Physiopathological Implications
Endocrinology, October 1, 2003; 144(10): 4315 - 4324.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online