Physiol Rev Watch the video to see how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Physiol. Rev. 81: 1269-1304, 2001;
0031-9333/01 $15.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (495)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Aranda, A.
Right arrow Articles by Pascual, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Aranda, A.
Right arrow Articles by Pascual, A.

Physiological Reviews, Vol. 81, No. 3, July 2001, pp. 1269-1304
Copyright ©2001 by the American Physiological Society

Nuclear Hormone Receptors and Gene Expression

Ana Aranda and Angel Pascual

Instituto de Investigaciones Biomédicas "Alberto Sols," Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain

Aranda, Ana and Angel Pascual. Nuclear Hormone Receptors and Gene Expression. Physiol. Rev. 81: 1269-1304, 2001.The nuclear hormone receptor superfamily includes receptors for thyroid and steroid hormones, retinoids and vitamin D, as well as different "orphan" receptors of unknown ligand. Ligands for some of these receptors have been recently identified, showing that products of lipid metabolism such as fatty acids, prostaglandins, or cholesterol derivatives can regulate gene expression by binding to nuclear receptors. Nuclear receptors act as ligand-inducible transcription factors by directly interacting as monomers, homodimers, or heterodimers with the retinoid X receptor with DNA response elements of target genes, as well as by "cross-talking" to other signaling pathways. The effects of nuclear receptors on transcription are mediated through recruitment of coregulators. A subset of receptors binds corepressor factors and actively represses target gene expression in the absence of ligand. Corepressors are found within multicomponent complexes that contain histone deacetylase activity. Deacetylation leads to chromatin compactation and transcriptional repression. Upon ligand binding, the receptors undergo a conformational change that allows the recruitment of multiple coactivator complexes. Some of these proteins are chromatin remodeling factors or possess histone acetylase activity, whereas others may interact directly with the basic transcriptional machinery. Recruitment of coactivator complexes to the target promoter causes chromatin decompactation and transcriptional activation. The characterization of corepressor and coactivator complexes, in concert with the identification of the specific interaction motifs in the receptors, has demonstrated the existence of a general molecular mechanism by which different receptors elicit their transcriptional responses in target genes.




This article has been cited by other articles:


Home page
 FASEB J.Home page
F. Tippmann, J. Hundt, A. Schneider, K. Endres, and F. Fahrenholz
Up-regulation of the {alpha}-secretase ADAM10 by retinoic acid receptors and acitretin
FASEB J, June 1, 2009; 23(6): 1643 - 1654.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. Ishimoto, T. Sakai, and T. Kitamoto
Ecdysone signaling regulates the formation of long-term courtship memory in adult Drosophila melanogaster
PNAS, April 14, 2009; 106(15): 6381 - 6386.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
K. Klein, G. A. Kullak-Ublick, M. Wagner, M. Trauner, and J. J. Eloranta
Hepatocyte nuclear factor-4{alpha} and bile acids regulate human concentrative nucleoside transporter-1 gene expression
Am J Physiol Gastrointest Liver Physiol, April 1, 2009; 296(4): G936 - G947.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
O. Martinez-Iglesias, S. Garcia-Silva, S. P. Tenbaum, J. Regadera, F. Larcher, J. M. Paramio, B. Vennstrom, and A. Aranda
Thyroid Hormone Receptor {beta}1 Acts as a Potent Suppressor of Tumor Invasiveness and Metastasis
Cancer Res., January 15, 2009; 69(2): 501 - 509.
[Abstract] [Full Text] [PDF]

Home page
 Mol Cancer ResHome page
J. Lai, S. A. Myers, M. G. Lawrence, D. M. Odorico, and J. A. Clements
Direct Progesterone Receptor and Indirect Androgen Receptor Interactions with the Kallikrein-Related Peptidase 4 Gene Promoter in Breast and Prostate Cancer
Mol. Cancer Res., January 1, 2009; 7(1): 129 - 141.
[Abstract] [Full Text] [PDF]

Home page
 Mol Cancer ResHome page
V. Duong, C. Bret, L. Altucci, A. Mai, C. Duraffourd, J. Loubersac, P.-O. Harmand, S. Bonnet, S. Valente, T. Maudelonde, et al.
Specific Activity of Class II Histone Deacetylases in Human Breast Cancer Cells
Mol. Cancer Res., December 1, 2008; 6(12): 1908 - 1919.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
V. Bombail, S. MacPherson, H. O.D. Critchley, and P. T.K. Saunders
Estrogen receptor related beta is expressed in human endometrium throughout the normal menstrual cycle
Hum. Reprod., December 1, 2008; 23(12): 2782 - 2790.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
A. Chiloeches, A. Sanchez-Pacheco, B. Gil-Araujo, A. Aranda, and M. Lasa
Thyroid Hormone-Mediated Activation of the ERK/Dual Specificity Phosphatase 1 Pathway Augments the Apoptosis of GH4C1 Cells by Down-Regulating Nuclear Factor-{kappa}B Activity
Mol. Endocrinol., November 1, 2008; 22(11): 2466 - 2480.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. Doni, G. Mantovani, C. Porta, J. Tuckermann, H. M. Reichardt, A. Kleiman, M. Sironi, L. Rubino, F. Pasqualini, M. Nebuloni, et al.
Cell-specific Regulation of PTX3 by Glucocorticoid Hormones in Hematopoietic and Nonhematopoietic Cells
J. Biol. Chem., October 31, 2008; 283(44): 29983 - 29992.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
V. T. Todorov, M. Desch, T. Schubert, and A. Kurtz
The Pal3 Promoter Sequence Is Critical for the Regulation of Human Renin Gene Transcription by Peroxisome Proliferator-Activated Receptor-{gamma}
Endocrinology, September 1, 2008; 149(9): 4647 - 4657.
[Abstract] [Full Text] [PDF]

Home page
 J. Bacteriol.Home page
A. Jahoor, R. Patel, A. Bryan, C. Do, J. Krier, C. Watters, W. Wahli, G. Li, S. C. Williams, and K. P. Rumbaugh
Peroxisome Proliferator-Activated Receptors Mediate Host Cell Proinflammatory Responses to Pseudomonas aeruginosa Autoinducer
J. Bacteriol., July 1, 2008; 190(13): 4408 - 4415.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
M. T. Sonoda, L. Martinez, P. Webb, M. S. Skaf, and I. Polikarpov
Ligand Dissociation from Estrogen Receptor Is Mediated by Receptor Dimerization: Evidence from Molecular Dynamics Simulations
Mol. Endocrinol., July 1, 2008; 22(7): 1565 - 1578.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
X. Rui, J. Tsao, J. O. Scheys, G. D. Hammer, and B. P. Schimmer
Contributions of Specificity Protein-1 and Steroidogenic Factor 1 to Adcy4 Expression in Y1 Mouse Adrenal Cells
Endocrinology, July 1, 2008; 149(7): 3668 - 3678.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
M. Nakanishi, Y. Tomaru, H. Miura, Y. Hayashizaki, and M. Suzuki
Identification of transcriptional regulatory cascades in retinoic acid-induced growth arrest of HepG2 cells
Nucleic Acids Res., June 1, 2008; 36(10): 3443 - 3454.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
I. Kuipers, P. van der Harst, G. Navis, L. van Genne, F. Morello, W. H. van Gilst, D. J. van Veldhuisen, and R. A. de Boer
Nuclear Hormone Receptors as Regulators of the Renin-Angiotensin-Aldosterone System
Hypertension, June 1, 2008; 51(6): 1442 - 1448.
[Full Text] [PDF]

Home page
 Reproductive SciencesHome page
B. Root, J. Abrassart, D. A. Myers, T. Monau, and C. A. Ducsay
Expression and Distribution of Glucocorticoid Receptors in the Ovine Fetal Adrenal Cortex: Effect of Long-term Hypoxia
Reproductive Sciences, May 1, 2008; 15(5): 517 - 528.
[Abstract] [PDF]

Home page
 EndocrinologyHome page
T. Asua, A. Bilbao, M. A. Gorriti, J. A. Lopez-Moreno, M. del Mar Alvarez, M. Navarro, F. Rodriguez de Fonseca, A. Perez-Castillo, and A. Santos
Implication of the Endocannabinoid System in the Locomotor Hyperactivity Associated with Congenital Hypothyroidism
Endocrinology, May 1, 2008; 149(5): 2657 - 2666.
[Abstract] [Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
S. Bondioni, A. R. Angioni, S. Corbetta, M. Locatelli, S. Ferrero, E. Ferrante, G. Mantovani, L. Olgiati, P. Beck-Peccoz, A. Spada, et al.
Effect of 9-cis Retinoic Acid on Dopamine D2 Receptor Expression in Pituitary Adenoma Cells
Experimental Biology and Medicine, April 1, 2008; 233(4): 439 - 446.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
A. Cohen, M. Shmoish, L. Levi, U. Cheruti, B. Levavi-Sivan, and E. Lubzens
Alterations in Micro-Ribonucleic Acid Expression Profiles Reveal a Novel Pathway for Estrogen Regulation
Endocrinology, April 1, 2008; 149(4): 1687 - 1696.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
H. Chen, M. Hewison, and J. S. Adams
Control of Estradiol-Directed Gene Transactivation by an Intracellular Estrogen-Binding Protein and an Estrogen Response Element-Binding Protein
Mol. Endocrinol., March 1, 2008; 22(3): 559 - 569.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
C. Montessuit, I. Papageorgiou, and R. Lerch
Nuclear Receptor Agonists Improve Insulin Responsiveness in Cultured Cardiomyocytes through Enhanced Signaling and Preserved Cytoskeletal Architecture
Endocrinology, March 1, 2008; 149(3): 1064 - 1074.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
S. Shrivastav, T. Kino, T. Cunningham, T. Ichijo, U. Schubert, P. Heinklein, G. P. Chrousos, and J. B. Kopp
Human Immunodeficiency Virus (HIV)-1 Viral Protein R Suppresses Transcriptional Activity of Peroxisome Proliferator-Activated Receptor {gamma} and Inhibits Adipocyte Differentiation: Implications for HIV-Associated Lipodystrophy
Mol. Endocrinol., February 1, 2008; 22(2): 234 - 247.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
G. Schafer, C. Wissmann, J. Hertel, V. Lunyak, and M. Hocker
Regulation of Vascular Endothelial Growth Factor D by Orphan Receptors Hepatocyte Nuclear Factor-4{alpha} and Chicken Ovalbumin Upstream Promoter Transcription Factors 1 and 2
Cancer Res., January 15, 2008; 68(2): 457 - 466.
[Abstract] [Full Text] [PDF]

Home page
 Endocr Relat CancerHome page
M. De los Santos, O. Martinez-Iglesias, and A. Aranda
Anti-estrogenic actions of histone deacetylase inhibitors in MCF-7 breast cancer cells
Endocr. Relat. Cancer, December 1, 2007; 14(4): 1021 - 1028.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
M. J. Hickman and F. Winston
Heme Levels Switch the Function of Hap1 of Saccharomyces cerevisiae between Transcriptional Activator and Transcriptional Repressor
Mol. Cell. Biol., November 1, 2007; 27(21): 7414 - 7424.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
R. Alzamora, L. R. Brown, and B. J. Harvey
Direct Binding and Activation of Protein Kinase C Isoforms by Aldosterone and 17{beta}-Estradiol
Mol. Endocrinol., November 1, 2007; 21(11): 2637 - 2650.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
S. Das, M. Schapira, M. Tomic-Canic, R. Goyanka, T. Cardozo, and H. H. Samuels
Farnesyl Pyrophosphate Is a Novel Transcriptional Activator for a Subset of Nuclear Hormone Receptors
Mol. Endocrinol., November 1, 2007; 21(11): 2672 - 2686.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
D. Li, Q. Kang, and D.-M. Wang
Constitutive Coactivator of Peroxisome Proliferator-Activated Receptor (PPAR{gamma}), a Novel Coactivator of PPAR{gamma} that Promotes Adipogenesis
Mol. Endocrinol., October 1, 2007; 21(10): 2320 - 2333.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
M. De los Santos, A. Zambrano, A. Sanchez-Pacheco, and A. Aranda
Histone Deacetylase Inhibitors Regulate Retinoic Acid Receptor {beta} Expression in Neuroblastoma Cells by Both Transcriptional and Posttranscriptional Mechanisms
Mol. Endocrinol., October 1, 2007; 21(10): 2416 - 2426.
[Abstract] [Full Text] [PDF]

Home page
 Stem CellsHome page
P. Luo, A. Wang, K. J. Payne, H. Peng, J.-g. Wang, Y. K. Parrish, J. W. Rogerio, T. J. Triche, Q. He, and L. Wu
Intrinsic Retinoic Acid Receptor {alpha}-Cyclin-Dependent Kinase-Activating Kinase Signaling Involves Coordination of the Restricted Proliferation and Granulocytic Differentiation of Human Hematopoietic Stem Cells
Stem Cells, October 1, 2007; 25(10): 2628 - 2637.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Z. Xu, O. L. Tavares-Sanchez, Q. Li, J. Fernando, C. M. Rodriguez, E. J. Studer, W. M. Pandak, P. B. Hylemon, and G. Gil
Activation of Bile Acid Biosynthesis by the p38 Mitogen-activated Protein Kinase (MAPK): HEPATOCYTE NUCLEAR FACTOR-4{alpha} PHOSPHORYLATION BY THE p38 MAPK IS REQUIRED FOR CHOLESTEROL 7{alpha}-HYDROXYLASE EXPRESSION
J. Biol. Chem., August 24, 2007; 282(34): 24607 - 24614.
[Abstract] [Full Text] [PDF]

Home page
 J Mol EndocrinolHome page
D. Nonclercq, F. Journe, I. Laios, C. Chaboteaux, R.-A. Toillon, G. Leclercq, and G. Laurent
Effect of nuclear export inhibition on estrogen receptor regulation in breast cancer cells
J. Mol. Endocrinol., August 1, 2007; 39(2): 105 - 118.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
M. A. Mahajan, A. Murray, D. Levy, and H. H. Samuels
Nuclear Receptor Coregulator (NRC): Mapping of the Dimerization Domain, Activation of p53 and STAT-2, and Identification of the Activation Domain AD2 Necessary for Nuclear Receptor Signaling
Mol. Endocrinol., August 1, 2007; 21(8): 1822 - 1834.
[Abstract] [Full Text] [PDF]

Home page
 GENES CELLSHome page
T. Kubota, S. Maezawa, K. Koiwai, T. Hayano, and O. Koiwai
Identification of functional domains in TdIF1 and its inhibitory mechanism for TdT activity
Genes Cells, August 1, 2007; 12(8): 941 - 959.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
S. Seoane, I. Ben, V. Centeno, and R. Perez-Fernandez
Cellular Expression Levels of the Vitamin D Receptor Are Critical to Its Transcriptional Regulation by the Pituitary Transcription Factor Pit-1
Mol. Endocrinol., July 1, 2007; 21(7): 1513 - 1525.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
J. R. Schultz-Norton, K. A. Walt, Y. S. Ziegler, I. X. McLeod, J. R. Yates, L. T. Raetzman, and A. M. Nardulli
The Deoxyribonucleic Acid Repair Protein Flap Endonuclease-1 Modulates Estrogen-Responsive Gene Expression
Mol. Endocrinol., July 1, 2007; 21(7): 1569 - 1580.
[Abstract] [Full Text] [PDF]

Home page
 J Mol EndocrinolHome page
J. Nevado, S. P Tenbaum, A. I. Castillo, A. Sanchez-Pacheco, and A. Aranda
Activation of the human immunodeficiency virus type I long terminal repeat by 1{alpha},25-dihydroxyvitamin D3
J. Mol. Endocrinol., June 1, 2007; 38(6): 587 - 601.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol PatholHome page
C. G. Woods, J. P. Vanden Heuvel, and I. Rusyn
Genomic Profiling in Nuclear Receptor-Mediated Toxicity
Toxicol Pathol, June 1, 2007; 35(4): 474 - 494.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
E. E. Connor, M. J. Meyer, R. W. Li, M. E. Van Amburgh, Y. R. Boisclair, and A. V. Capuco
Regulation of Gene Expression in the Bovine Mammary Gland by Ovarian Steroids
J Dairy Sci, June 1, 2007; 90(13_suppl): E55 - E65.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
A. Haelens, T. Tanner, S. Denayer, L. Callewaert, and F. Claessens
The Hinge Region Regulates DNA Binding, Nuclear Translocation, and Transactivation of the Androgen Receptor
Cancer Res., May 1, 2007; 67(9): 4514 - 4523.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. Genini and C. V. Catapano
Block of Nuclear Receptor Ubiquitination: A MECHANISM OF LIGAND-DEPENDENT CONTROL OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR {delta} ACTIVITY
J. Biol. Chem., April 20, 2007; 282(16): 11776 - 11785.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
W. Wente, M. B. Brenner, H. Zitzer, J. Gromada, and A. M. Efanov
Activation of Liver X Receptors and Retinoid X Receptors Induces Growth Arrest and Apoptosis in Insulin-Secreting Cells
Endocrinology, April 1, 2007; 148(4): 1843 - 1849.
[Abstract] [Full Text] [PDF]

Home page
 Molecular Cancer TherapeuticsHome page
M. De los Santos, A. Zambrano, and A. Aranda
Combined effects of retinoic acid and histone deacetylase inhibitors on human neuroblastoma SH-SY5Y cells
Mol. Cancer Ther., April 1, 2007; 6(4): 1425 - 1432.
[Abstract] [Full Text] [PDF]

Home page
 Adv. Physiol. Educ.Home page
K. M. Eyster
The membrane and lipids as integral participants in signal transduction: lipid signal transduction for the non-lipid biochemist
Advan Physiol Educ, March 1, 2007; 31(1): 5 - 16.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
E. Bonnelye, R. A. Zirngibl, P. Jurdic, and J. E. Aubin
The Orphan Nuclear Estrogen Receptor-Related Receptor-{alpha} Regulates Cartilage Formation in Vitro: Implication of Sox9
Endocrinology, March 1, 2007; 148(3): 1195 - 1205.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Wang, C. Zhang, S. K. Nordeen, and D. J. Shapiro
In Vitro Fluorescence Anisotropy Analysis of the Interaction of Full-length SRC1a with Estrogen Receptors {alpha} and beta Supports an Active Displacement Model for Coregulator Utilization
J. Biol. Chem., February 2, 2007; 282(5): 2765 - 2775.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
R. Kitazawa and S. Kitazawa
Methylation Status of a Single CpG Locus 3 Bases Upstream of TATA-Box of Receptor Activator of Nuclear Factor-{kappa}B Ligand (RANKL) Gene Promoter Modulates Cell- and Tissue-Specific RANKL Expression and Osteoclastogenesis
Mol. Endocrinol., January 1, 2007; 21(1): 148 - 158.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
C. M. Kusminski, N. F. da Silva, S. J. Creely, F. M. Fisher, A. L. Harte, A. R. Baker, S. Kumar, and P. G. McTernan
The in Vitro Effects of Resistin on the Innate Immune Signaling Pathway in Isolated Human Subcutaneous Adipocytes
J. Clin. Endocrinol. Metab., January 1, 2007; 92(1): 270 - 276.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
H.-T. Kim, G. Kong, D. DeNardo, Y. Li, I. Uray, S. Pal, S. Mohsin, S. G. Hilsenbeck, R. Bissonnette, W. W. Lamph, et al.
Identification of Biomarkers Modulated by the Rexinoid LGD1069 (Bexarotene) in Human Breast Cells Using Oligonucleotide Arrays
Cancer Res., December 15, 2006; 66(24): 12009 - 12018.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
L. Fang, D. Ricketson, L. Getubig, and B. Darimont
Unliganded and hormone-bound glucocorticoid receptors interact with distinct hydrophobic sites in the Hsp90 C-terminal domain
PNAS, December 5, 2006; 103(49): 18487 - 18492.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
P. Germain, P. Chambon, G. Eichele, R. M. Evans, M. A. Lazar, M. Leid, A. R. De Lera, R. Lotan, D. J. Mangelsdorf, and H. Gronemeyer
International Union of Pharmacology. LX. Retinoic Acid Receptors
Pharmacol. Rev., December 1, 2006; 58(4): 712 - 725.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
A. I. Castillo, R. Sanchez-Martinez, A. M. Jimenez-Lara, A. Steinmeyer, U. Zugel, and A. Aranda
Characterization of Vitamin D Receptor Ligands with Cell-Specific and Dissociated Activity
Mol. Endocrinol., December 1, 2006; 20(12): 3093 - 3104.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
J. Mercader, J. Ribot, I. Murano, F. Felipe, S. Cinti, M. L. Bonet, and A. Palou
Remodeling of White Adipose Tissue after Retinoic Acid Administration in Mice
Endocrinology, November 1, 2006; 147(11): 5325 - 5332.
[Abstract] [Full Text] [PDF]

Home page
 CarcinogenesisHome page
M. Wirtenberger, S. Tchatchou, K. Hemminki, J. Schmutzhard, C. Sutter, R. K. Schmutzler, A. Meindl, B. Wappenschmidt, M. Kiechle, N. Arnold, et al.
Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer
Carcinogenesis, November 1, 2006; 27(11): 2201 - 2208.
[Abstract] [Full Text] [PDF]

Home page
 J EndocrinolHome page
T. Maruyama, K. Tanaka, J. Suzuki, H. Miyoshi, N. Harada, T. Nakamura, Y. Miyamoto, A. Kanatani, and Y. Tamai
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
J. Endocrinol., October 1, 2006; 191(1): 197 - 205.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
A. K. Iyer, Y.-H. Zhang, and E. R. B. McCabe
Dosage-Sensitive Sex Reversal Adrenal Hypoplasia Congenita Critical Region on the X Chromosome, Gene 1 (DAX1) (NR0B1) and Small Heterodimer Partner (SHP) (NR0B2) Form Homodimers Individually, as Well as DAX1-SHP Heterodimers
Mol. Endocrinol., October 1, 2006; 20(10): 2326 - 2342.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
M. J. Brayman, J. Julian, B. Mulac-Jericevic, O. M. Conneely, D. P. Edwards, and D. D. Carson
Progesterone Receptor Isoforms A and B Differentially Regulate MUC1 Expression in Uterine Epithelial Cells
Mol. Endocrinol., October 1, 2006; 20(10): 2278 - 2291.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
J.-g. Wang, L. W. Barsky, E. Davicioni, K. I. Weinberg, T. J. Triche, X.-k. Zhang, and L. Wu
Retinoic acid induces leukemia cell G1 arrest and transition into differentiation by inhibiting cyclin-dependent kinase-activating kinase binding and phosphorylation of PML/RAR{alpha}
FASEB J, October 1, 2006; 20(12): 2142 - 2144.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
H. Tian, M. A. Mahajan, C. T. Wong, I. Habeos, and H. H. Samuels
The N-Terminal A/B Domain of the Thyroid Hormone Receptor-{beta}2 Isoform Influences Ligand-Dependent Recruitment of Coactivators to the Ligand-Binding Domain
Mol. Endocrinol., September 1, 2006; 20(9): 2036 - 2051.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
A. G. Smith and G. E. O. Muscat
Orphan nuclear receptors: therapeutic opportunities in skeletal muscle
Am J Physiol Cell Physiol, August 1, 2006; 291(2): C203 - C217.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Pharmacol.Home page
H. Tozaki-Saitoh, S. Koizumi, Y. Sato, M. Tsuda, T. Nagao, and K. Inoue
Retinoic Acids Increase P2X2 Receptor Expression through the 5'-Flanking Region of P2rx2 Gene in Rat Phaeochromocytoma PC-12 Cells
Mol. Pharmacol., July 1, 2006; 70(1): 319 - 328.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Takayama, I. Rogatsky, L. E. Schwarcz, and B. D. Darimont
The Glucocorticoid Receptor Represses Cyclin D1 by Targeting the Tcf-beta-Catenin Complex
J. Biol. Chem., June 30, 2006; 281(26): 17856 - 17863.
[Abstract] [Full Text] [PDF]

Home page
 Sci SignalHome page
L. A. Arnold, E. Estebanez-Perpina, M. Togashi, A. Shelat, C. A. Ocasio, A. C. McReynolds, P. Nguyen, J. D. Baxter, R. J. Fletterick, P. Webb, et al.
A High-Throughput Screening Method to Identify Small Molecule Inhibitors of Thyroid Hormone Receptor Coactivator Binding
Sci. Signal., June 27, 2006; 2006(341): pl3 - pl3.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
B. Desvergne, L. Michalik, and W. Wahli
Transcriptional Regulation of Metabolism
Physiol Rev, April 1, 2006; 86(2): 465 - 514.
[Abstract] [Full Text] [PDF]

Home page
 JEMHome page
H. Zeng, L. Qin, D. Zhao, X. Tan, E. J. Manseau, M. Van Hoang, D. R. Senger, L. F. Brown, J. A. Nagy, and H. F. Dvorak
Orphan nuclear receptor TR3/Nur77 regulates VEGF-A-induced angiogenesis through its transcriptional activity
J. Exp. Med., March 20, 2006; 203(3): 719 - 729.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Z. Gao, Q. He, B. Peng, P. J. Chiao, and J. Ye
Regulation of Nuclear Translocation of HDAC3 by I{kappa}B{alpha} Is Required for Tumor Necrosis Factor Inhibition of Peroxisome Proliferator-activated Receptor {gamma} Function
J. Biol. Chem., February 17, 2006; 281(7): 4540 - 4547.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
V. R. Holla, J. R. Mann, Q. Shi, and R. N. DuBois
Prostaglandin E2 Regulates the Nuclear Receptor NR4A2 in Colorectal Cancer
J. Biol. Chem., February 3, 2006; 281(5): 2676 - 2682.
[Abstract] [Full Text] [PDF]

Home page
 J Mol EndocrinolHome page
C.-C. Yen, Y.-H. Huang, C.-Y. Liao, C.-J. Liao, W.-L. Cheng, W.-J. Chen, and K.-H. Lin
Mediation of the inhibitory effect of thyroid hormone on proliferation of hepatoma cells by transforming growth factor-beta
J. Mol. Endocrinol., February 1, 2006; 36(1): 9 - 21.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
S Corbetta, R Angioni, A Cattaneo, P Beck-Peccoz, and A Spada
Effects of retinoid therapy on insulin sensitivity, lipid profile and circulating adipocytokines
Eur. J. Endocrinol., January 1, 2006; 154(1): 83 - 86.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
A. Guerrieri-Gonzaga, C. Robertson, B. Bonanni, D. Serrano, M. Cazzaniga, S. Mora, M. Gulisano, H. Johansson, F. Formelli, M. Intra, et al.
Preliminary Results on Safety and Activity of a Randomized, Double-Blind, 2 x 2 Trial of Low-Dose Tamoxifen and Fenretinide for Breast Cancer Prevention in Premenopausal Women
J. Clin. Oncol., January 1, 2006; 24(1): 129 - 135.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. Zhang, X. Xie, X. Zhu, J. Zhu, C. Hao, Q. Lu, L. Ding, Y. Liu, L. Zhou, Y. Liu, et al.
Stimulatory Cross-talk between NFAT3 and Estrogen Receptor in Breast Cancer Cells
J. Biol. Chem., December 30, 2005; 280(52): 43188 - 43197.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
L. A. Arnold, E. Estebanez-Perpina, M. Togashi, N. Jouravel, A. Shelat, A. C. McReynolds, E. Mar, P. Nguyen, J. D. Baxter, R. J. Fletterick, et al.
Discovery of Small Molecule Inhibitors of the Interaction of the Thyroid Hormone Receptor with Transcriptional Coregulators
J. Biol. Chem., December 30, 2005; 280(52): 43048 - 43055.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. Yasmin, R. M. Williams, M. Xu, and N. Noy
Nuclear Import of the Retinoid X Receptor, the Vitamin D Receptor, and Their Mutual Heterodimer
J. Biol. Chem., December 2, 2005; 280(48): 40152 - 40160.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
B. T. Vander Kooi, H. Onuma, J. K. Oeser, C. A. Svitek, S. R. Allen, C. W. Vander Kooi, W. J. Chazin, and R. M. O'Brien
The Glucose-6-Phosphatase Catalytic Subunit Gene Promoter Contains Both Positive and Negative Glucocorticoid Response Elements
Mol. Endocrinol., December 1, 2005; 19(12): 3001 - 3022.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
K. Okamoto and F. Isohashi
Macromolecular Translocation Inhibitor II (Zn2+-binding Protein, Parathymosin) Interacts with the Glucocorticoid Receptor and Enhances Transcription in Vivo
J. Biol. Chem., November 4, 2005; 280(44): 36986 - 36993.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
H. Karst and M. Joels
Corticosterone Slowly Enhances Miniature Excitatory Postsynaptic Current Amplitude in Mice CA1 Hippocampal Cells
J Neurophysiol, November 1, 2005; 94(5): 3479 - 3486.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
T.-T. Wang, L. E. Tavera-Mendoza, D. Laperriere, E. Libby, N. Burton MacLeod, Y. Nagai, V. Bourdeau, A. Konstorum, B. Lallemant, R. Zhang, et al.
Large-Scale in Silico and Microarray-Based Identification of Direct 1,25-Dihydroxyvitamin D3 Target Genes
Mol. Endocrinol., November 1, 2005; 19(11): 2685 - 2695.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
H. Kawate, Y. Wu, K. Ohnaka, R.-H. Tao, K.-i. Nakamura, T. Okabe, T. Yanase, H. Nawata, and R. Takayanagi
Impaired Nuclear Translocation, Nuclear Matrix Targeting, and Intranuclear Mobility of Mutant Androgen Receptors Carrying Amino Acid Substitutions in the Deoxyribonucleic Acid-Binding Domain Derived from Androgen Insensitivity Syndrome Patients
J. Clin. Endocrinol. Metab., November 1, 2005; 90(11): 6162 - 6169.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
N. Devidze, J. A. Mong, A. M. Jasnow, L.-M. Kow, and D. W. Pfaff
Sex and estrogenic effects on coexpression of mRNAs in single ventromedial hypothalamic neurons
PNAS, October 4, 2005; 102(40): 14446 - 14451.
[Abstract] [Full Text] [PDF]

Home page
 J EndocrinolHome page
M S Fernandes, V Pierron, D Michalovich, S Astle, S Thornton, H Peltoketo, E W-F Lam, B Gellersen, I Huhtaniemi, J Allen, et al.
Regulated expression of putative membrane progestin receptor homologues in human endometrium and gestational tissues
J. Endocrinol., October 1, 2005; 187(1): 89 - 101.
[Abstract] [Full Text] [PDF]

Home page
 J BiochemHome page
Y. Inayoshi, H. Kaneoka, Y. Machida, M. Terajima, T. Dohda, K. Miyake, and S. Iijima
Repression of GR-Mediated Expression of the Tryptophan Oxygenase Gene by the SWI/SNF Complex during Liver Development
J. Biochem., October 1, 2005; 138(4): 457 - 465.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Gu, D. H. Morgan, M. Sattar, X. Xu, R. Wagner, M. Raviscioni, O. Lichtarge, and A. J. Cooney
Evolutionary Trace-based Peptides Identify a Novel Asymmetric Interaction That Mediates Oligomerization in Nuclear Receptors
J. Biol. Chem., September 9, 2005; 280(36): 31818 - 31829.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
A. Archer, D. Sauvaget, V. Chauffeton, P.-E. Bouchet, J. Chambaz, M. Pincon-Raymond, P. Cardot, A. Ribeiro, and M. Lacasa
Intestinal Apolipoprotein A-IV Gene Transcription Is Controlled by Two Hormone-Responsive Elements: A Role for Hepatic Nuclear Factor-4 Isoforms
Mol. Endocrinol., September 1, 2005; 19(9): 2320 - 2334.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
S. J. Marx and W. F. Simonds
Hereditary Hormone Excess: Genes, Molecular Pathways, and Syndromes
Endocr. Rev., August 1, 2005; 26(5): 615 - 661.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. Moayeri, J. I. Webster, J. F. Wiggins, S. H. Leppla, and E. M. Sternberg
Endocrine Perturbation Increases Susceptibility of Mice to Anthrax Lethal Toxin
Infect. Immun., July 1, 2005; 73(7): 4238 - 4244.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
P. Rajatapiti, M. H. A. Kester, R. R. de Krijger, R. Rottier, T. J. Visser, and D. Tibboel
Expression of Glucocorticoid, Retinoid, and Thyroid Hormone Receptors during Human Lung Development
J. Clin. Endocrinol. Metab., July 1, 2005; 90(7): 4309 - 4314.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
C. M. Stapleton, M. Jaradat, D. Dixon, H. S. Kang, S.-C. Kim, G. Liao, M. A. Carey, J. Cristiano, M. P. Moorman, and A. M. Jetten
Enhanced susceptibility of staggerer (ROR{alpha}sg/sg) mice to lipopolysaccharide-induced lung inflammation
Am J Physiol Lung Cell Mol Physiol, July 1, 2005; 289(1): L144 - L152.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. Luna-Medina, M. Cortes-Canteli, M. Alonso, A. Santos, A. Martinez, and A. Perez-Castillo
Regulation of Inflammatory Response in Neural Cells in Vitro by Thiadiazolidinones Derivatives through Peroxisome Proliferator-activated Receptor {gamma} Activation
J. Biol. Chem., June 3, 2005; 280(22): 21453 - 21462.
[Abstract] [Full Text] [PDF]

Home page
 J Mol EndocrinolHome page
C Feart, J Vallortigara, D Higueret, B Gatta, A Tabarin, V Enderlin, P Higueret, and V Pallet
Decreased expression of retinoid nuclear receptor (RAR{alpha} and RAR{gamma}) mRNA determined by real-time quantitative RT-PCR in peripheral blood mononuclear cells of hypothyroid patients
J. Mol. Endocrinol., June 1, 2005; 34(3): 849 - 858.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
M. A. Mahajan and H. H. Samuels
Nuclear Hormone Receptor Coregulator: Role in Hormone Action, Metabolism, Growth, and Development
Endocr. Rev., June 1, 2005; 26(4): 583 - 597.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T.-C. Tsai, Y.-L. Lee, W.-C. Hsiao, Y.-P. Tsao, and S.-L. Chen
NRIP, a Novel Nuclear Receptor Interaction Protein, Enhances the Transcriptional Activity of Nuclear Receptors
J. Biol. Chem., May 20, 2005; 280(20): 20000 - 20009.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
H. Masuyama, N. Suwaki, Y. Tateishi, H. Nakatsukasa, T. Segawa, and Y. Hiramatsu
The Pregnane X Receptor Regulates Gene Expression in a Ligand- and Promoter- Selective Fashion
Mol. Endocrinol., May 1, 2005; 19(5): 1170 - 1180.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. Bour, J.-L. Plassat, A. Bauer, S. Lalevee, and C. Rochette-Egly
Vinexin {beta} Interacts with the Non-phosphorylated AF-1 Domain of Retinoid Receptor {gamma} (RAR{gamma}) and Represses RAR{gamma}-mediated Transcription
J. Biol. Chem., April 29, 2005; 280(17): 17027 - 17037.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
S. Scsucova, D. Palacios, M. Savignac, B. Mellstrom, J. R. Naranjo, and A. Aranda
The repressor DREAM acts as a transcriptional activator on Vitamin D and retinoic acid response elements
Nucleic Acids Res., April 22, 2005; 33(7): 2269 - 2279.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
C. B. Huppenbauer, L. Tanzer, L. L. DonCarlos, and K. J. Jones
Gonadal Steroid Attenuation of Developing Hamster Facial Motoneuron Loss by Axotomy: Equal Efficacy of Testosterone, Dihydrotestosterone, and 17-{beta} Estradiol
J. Neurosci., April 20, 2005; 25(16): 4004 - 4013.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
J. M. R. Moore and R. K. Guy
Coregulator Interactions with the Thyroid Hormone Receptor
Mol. Cell. Proteomics, April 1, 2005; 4(4): 475 - 482.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online